What is the best non-prescription analgesic/anti-inflammatory to take with lisinopril?

Pain pills, zestril (lisinopril): Lisinopril (l) has no known interactions with over the counter analgesics, so you need not worry about any. If you are taking nsaid's, you should know that they have the potential for acute renal failure, reversible when they are stopped, and may cause some change of bleeding from the stomach. Speak to the doctor who prescribed l for you.