A member asked:

What are the causes of macular degeneration?

10 doctors weighed in across 4 answers
Dr. Todd Purkiss answered

Specializes in Ophthalmology

Macular degeneration (amd) is primarily an age-related disease (age 50+), but there are genetic and environmental factors that contribute to age of onset and severity. Risk factors for cardiovascular disease (stroke, heart attack) are also risk factors for amd. Smoking is the top modifiable risk factor. Of course, there is a lot we still don't understand about amd.

Answered Feb 10, 2015

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Dr. Keshav Narain answered

Specializes in Retinal Surgery

This is the billion dollar question that is being answered by researchers across the globe. Generally, it is becoming evident that there are multiple genes involved in macular degenerations - both age related and other types. In addition to genetics, however, we know that there are some vital environmental factors that play a role. This includes photo-oxidation, antioxidant consumption and more.

Answered May 29, 2013

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Dr. Bruce Saran answered

Specializes in Ophthalmology

Macular degeneration is thought to occur from aging, exposure to uv radiation, exposure to toxins (smoking) and "pre-programmed" by genetics (family and race). You can lessen your risk by am early eye exam, don't smoke, shield your exposure from uv and follow your doctor's advice for nutrition and vitamins based on your age and exam. No prescribed drug yet.

Answered Jan 1, 2014

4.6k views

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Dr. Colin McCannel answered

Specializes in Retinal Surgery

The predisposition for macular degeneration is inherited. It is a very complex disease with several, if not many genetic mutations contributing to risk. Additionally, there are other health factors that modulate disease risk. Most importantly nutrition, but also life style (smoking=bad), etc. Rule of thumb: if something is thought to be good for the heart, it probably also reduces amd risk.

Answered May 22, 2015

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