Long term effects from epidural steroid injections?

Sometimes: Sometimes long term cure. Rarely, chemical injury can occur. Remember that steroids are like real estate: it's all location.

Mulitple Effects: Weight gain, avascular necrosis of a hip/knee (severe breakdown requiring joint replacement), hair loss, adrenal suppression. However, these side effects are rare. Nonetheless, you must consider with your physician risks versus benefits of steroids or any treatment option considered. Epidural steroid injections can provide the right patient with significant relief of symptoms.

Pain relief: On the positive side the effect would be less pain and greater quality of life. Long term adverse effects are minimal.