A member asked:

I have question, why during dna/rna pcr test scientist use dried blood spot(dbs) to diagnose hiv but at the same time they say hiv is inactive in the dried blood so they test active hiv particle or inactive hiv particle?

Q: i have question, why during dna/rna pcr test scientist use dried blood spot(dbs) to diagnose hiv but at the same time they say hiv is inactive in the dried blood so they test active hiv particle or inactive hiv particle?

: Detection of HIV RNA is dried blood for diagnosis is entirely different than survival of live virus that can be transmitted. It does not take "active" HIV particles to give a positive RNA test. And transmission of infection requires exposure of millions of virus particles to particular cells deep inside the body.

A doctor has provided 1 answer

Dr. Hunter Handsfield answered

Specializes in Infectious Disease

Detection of HIV RNA is dried blood for diagnosis is entirely different than survival of live virus that can be transmitted. It does not take "active" HIV particles to give a positive RNA test. And transmission of infection requires exposure of millions of virus particles to particular cells deep inside the body.

Answered 8/5/2023

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A member asked:

I have question, why during dna/rna pcr test scientist use dried blood spot(dbs) to diagnose hiv but at the same time they say hiv is inactive in the dried blood so they test active hiv particle or inactive hiv particle?

A doctor has provided 1 answer

Dr. Hunter Handsfield answered

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