A member asked:

On zoloft for 10yrs. doc and i both believe i need to switch to lexapro. im nervous to do a direct switch which is stop zoloft and start lexapro 10mg the next day. thoughts?

A doctor has provided 1 answer
Dr. Leslie Leighton answered

Specializes in Internal Medicine

Should be no problem. Have done this on many patients without an issue as long as you start the lexapro the day after you take your last Zoloft. Numerous of my patients do very well with a switch to Lexapro.

Answered 7/21/2023

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