Start Lexapro (escitalopram): While still on the zoloft . I usually have someone start on a small dose of the Lexapro (escitalopram) and increase it gradually while at the same time, taper down even more slowly on the zoloft. Each new antidepressant essentially has to start over again and needs time to work. Therefore you don't want to go off the zoloft too quickly, you may find out it had been doing much more for you than you had thought.
Answered 7/4/2018
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