A member asked:

Get tested with hiv duo combo test after 30days which the value is 0.33 in 0.35 reference range .why the index value is too high. and i tested 135days after pep with 4th gen duo combo is this conclusive report .or i need to retest?

A doctor has provided 1 answer
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

You misunderstand the "reference range" and its meaning. If below the cut-off value (usually 0.9), the result is negative. Values of, say, 0.1, 0.3, 0.6, or 0.85 all are equally negative; they are not measures of small amounts of antibody. The exact same specimen tested 10 times will give 10 different numbers, which could vary from 0.1 to. 0.8, especially if tested with different lots of reagents.

Answered 5/3/2023

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