Is d mannose safe to take in first trimester?

D-mannose is a natural sugar found in health food stores marketed to prevent recurrent bladder infections. Unfortunately, there is lack of convincing clinical efficacy due to few and low quality studies. Furthermore, it is unknown whether it is harmful to human fetuses because of the lack of data. Caution or alternate treatment is advised

No. Taking such things should only be done if OK'd by the OB doc