Have had widespread nerve pain, fatigue, brain fog, spasms and twitching for about 2 years. normal head and c-spine mri, normal emg and nerve conduction study. what could it be? doc suggested spinal tap to look for inflammation - what could that find?

Have NO clue what your doctor is thinking, but do think this is a good idea for the next step. Discuss what specific tests are being ordered and what the diagnostic thoughts are.

Dr Seibert agreed

This is partly a duplicate question; see other reply. The main tests done on spinal fluid are for inflammation or infection, like white blood cell types and number, protein and glucose levels, and sometimes tests for particular infections (culture for bacteria, various viruses, syphilis if at risk, and others). Clarify with your doctor exactly what conditions are on her mind. Good luck.

Dr Machanic and another doctor agreed

For the listed symptoms a thorough Basic Work Up like- Labs to check for Diabetes and other Endocrine/Hormonal issues. What about Nutrition - Malnutrition/Poor Nutrition with Vitamin and Minerals Deficiency Syndromes? A good Comprehensive analysis when done can reveal much correctable underlying causes of these symptoms.

Dr Kuitems agreed