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A member asked:
I am taking omeprazole 20mg daily in the evening before a meal. i also must take methotrexate 2.5mg 1x/week for my arthritis at bedtime. safe to take both on the sunday evening? if not, what are my options?
A doctor has provided 1 answer
The omeprazole can increase the concentration of the methotrexate. Are you taking the methotrexate chronically or for a certain time interval? In lower doses, the increase in methotrexate concentration is less of an issue. If your doctor says to continue both medicines, then take the omeprazole with supper and take the methotrexate dose 2-4 hours later. Best of luck to you!
Answered 12/27/2022
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