A member asked:

I was reactive for rpr and negative for fta in september in april i was negative for both since then ive only had 2 sexual partners what does this mean should i start treatment for syphillis?

3 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

If you have syphilis, FTA will remain positive forever and RPR will be negative after your are successfully treated. RPR is only a screening test and false positive test is relatively common. No, you do not have syphilis. Please practice safe sex for avoiding STDs.

Answered 9/12/2022

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Dr. Hunter Handsfield answered

Specializes in Infectious Disease

You had a "biological false positive" RPR result; the negative FTA proves you do not have syphilis and never did. BFP is very common, occurring up to 2% of all positive RPR results, i.e. one in 50 persons. It has no health consideration, especially if it goes away on repeat testing. You should not be treated for syphilis; nothing is wrong.

Answered 9/12/2022

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