A member asked:

Can sibo cause high (2900) calprotectin? i have had cd and uc ruled out with colonoscopy?

A doctor has provided 1 answer
Dr. Hunter Handsfield answered

Specializes in Infectious Disease

SIBO is not a likely cause of elevated fecal calprotectin, especially at such a high level. Same for celiac disease (your other question). At this high level, the most likely explanation is inflammatory bowel disease (Crohn's, ulcerative colitis) that were missed by colonoscopy, such as Crohn's of the small intestine. Keep working with your doctor(s), including a gastroenterologist. Good luck.

Answered 9/11/2022

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