Trimethoprim-sulfamethoxazole (Bactrim DS) does not have kidney stones listed as a side effect or adverse effect. There are other verified side effects, please review the manufacturer insert that should be included with the prescription from the pharmacy. Adequate hydration is always best practice regardless.
Answered 7/16/2022
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Crystalluria (kidney stone may develop because of this) is a moderate side effect of Bactrim but the incidence is not known and I would say it is extremely rare by my personal experience. Because this side effect is preventable by drinking fluid well when taking this antibiotic so this practice has been recommended. If you drink adequately, you should be fine, do not worry much.
Answered 7/18/2022
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