A member asked:

Husband got his rft done back in oct 2021 and his createnine was 0.85 and urea was 21.9 which is a bit high.now he repeat test and createnine is 0.88 and urea is 16.is increase in createnine normal? his egfr declined from 100 to 97.is overweight?

3 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

Those changes are frequently seen. First, renal function is still normal by both blood tests. Second, the change is in the margin of lab variation when blood tests are done at different times. The GFR is just a calculation with a formula based on serum creatinine, age and gender.

Answered 3/7/2022

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All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, the change in results is not a meaningful change. Wish you good health!

Answered 3/11/2022

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