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A member asked:
I take 120 mg of methadone, but i've been sick the past few days. my mom bought me the daytime and nighttime of the nyquil. can i take it while on methadone?
A doctor has provided 1 answer
There is a moderate interaction between methadone and dextromethorphan which is an ingredient of nyquil. Use this combination increases the risk of a rare but serious condition called the serotonin syndrome. You should just take cold medicine OTC without dextromethorphan.
Answered 3/6/2022
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