A member asked:

I take 120 mg of methadone, but i've been sick the past few days. my mom bought me the daytime and nighttime of the nyquil. can i take it while on methadone?

Q: i take 120 mg of methadone, but i've been sick the past few days. my mom bought me the daytime and nighttime of the nyquil. can i take it while on methadone?

: There is a moderate interaction between methadone and dextromethorphan which is an ingredient of nyquil. Use this combination increases the risk of a rare but serious condition called the serotonin syndrome. You should just take cold medicine OTC without dextromethorphan.

A doctor has provided 1 answer

Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

There is a moderate interaction between methadone and dextromethorphan which is an ingredient of nyquil. Use this combination increases the risk of a rare but serious condition called the serotonin syndrome. You should just take cold medicine OTC without dextromethorphan.

Answered 3/6/2022

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A member asked:

I take 120 mg of methadone, but i've been sick the past few days. my mom bought me the daytime and nighttime of the nyquil. can i take it while on methadone?

A doctor has provided 1 answer

Dr. Hiep Le answered

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