A member asked:

What's the difference between taking prednisone once a day or multiple times a day? why spread it out?

Q: what's the difference between taking prednisone once a day or multiple times a day? why spread it out?

: The effect is not different for single or divided dose but the stomach tolerates divided dose better in case of very high dose.

2 doctors weighed in across 2 answers

Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

The effect is not different for single or divided dose but the stomach tolerates divided dose better in case of very high dose.

Dr Machanic agreed

Answered 2/28/2022

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Dr. Bennett Machanic answered

Many yrs ago, a study from Johns Hopkins Hospital noted a substantial decease in steroid side effects when ingested once daily as contrasted to twice or thrice daily

Answered 2/28/2022

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A member asked:

What's the difference between taking prednisone once a day or multiple times a day? why spread it out?

2 doctors weighed in across 2 answers

Dr. Hiep Le answered

Dr Machanic agreed

Dr. Bennett Machanic answered

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