A member asked:

Is cbd isolate with no thc be ok to mix with lithium and depakote? cbd taken for pain relief and sleep?

A doctor has provided 1 answer

Since Cannabidiol is metabolized via the cytochrome P450 system in the liver, caution is urged when taking anti-epileptic drugs, such as Depakote. Serum drug levels can be altered, and a blood test can reveal the effect. Lithium levels can also be measured, but CBD-lithium interactions appear not to be documented. Discuss further with prescribing doctor.

Answered 2/10/2022

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