Is it safe to take lorazepam with lunesta?

Would not see any medical rationale to mix the two. Likely side effects of drowsiness, dizziness, and perhaps mild confusion, potentially greater due to additive interactions. Higher doses would be more intense. Would not drive or use power equipment if this combination is ingested. Discuss with your primary care physician.

While lorazepam does cause drowsiness and sedation, benzodiazepines, the class that lorazepam belongs to, actually block stage IV sleep. The primary reason that we sleep is to get the restoration action afforded by stage IV sleep. Losing this stage of sleep is detrimental. For this reason benzodiazepines including lorazepam should never be used for sleep. They actually cause sleep problems.