My dates-creatinine/egfr(epi)/egfr(mdrd) are: 9/10-.93/70/63, 9/11-1.00/64/58, 7/12-1.24/48/45*, and 8/12-1.06/59/54. *results from diff lab. what action should be pursued? should i be concerned?

Yes: Assuming that these lab tests are in chronological order, you are showing some decrease in renal function over time. While different labs may show slightly different results, your last (8/12) result is trending downward. Your estimated GFR is now less than 60, and that is a sign of impaired renal function. You and your physician should review meds and other factors that could be modified..

EGFR limitations: You seem to be concerned with your varying estimated GFR (egfr) levels. You lab data shows only creatinine (levels). To find out your actual kidney function see a nephrologist (n) and have a 24 hour urine collection for a c clearance. This will give you your actual level of renal function, not an estimate. A n will let you know if you should or should not be worried about your kidney function.