Can you drink alcohol while using topical metrodinazole cream for acne on face? some websites say no while others say yes. does the topical application get in bloodstream?

Did you mean Metronidazole?. This is an antibiotic, it has no interaction with Alcohol. The chemical contained in any cream does often get into the blood stream but most times it is fairly harmless as the amount absorbed is very small.

Alcohol is a poison that never did anybody any good, ever, so stay away from it. It will destroy your brain cells, facilitate development of cancer in many organs, including breast, cause hepatitis, cirrhosis and pancreatitis etc. There is no safe level of alcohol intake. Quit while you are ahead.

The warning for the interaction between metronidazole and alcohol is for the oral form of the medication. There is not an interaction with the topical form, as little to none gets into the bloodstream.