Yes . The oestrogen in the contraceptive pills increases the level of a special blood protein called cortisol binding globulin , which causes an increase in the total cortisol level.This is dependent on the dose of oestrogen in the pill , and is mainly seen with high dose oestrogen pills with more than 0.1mg of mestranol , and not in the progesterone only or the ones with low dose oestrogen.
Answered 6/12/2021
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