My bro's recent labs show rbc's 3.84, hgb 10.9 and hct 33.5 w/ platelets 561. with such a low red count, hgb and hct how anemic is he and what does the high platelet count mean? he was diagnosed with sluders syndrome, migrane and takes aspirin a lot?

Sluder’s syndrome is facial pain due (maybe) to nerve irritation. Anemia should be unrelated. Your brother is significantly anemic (not dangerous - yet) and needs an evaluation by a primary care doc or hematologist. Maybe (MAYBE) the aspirin is causing stomach/intestinal upset with bleeding into his bowel, but that’s only a guess. Needs a better evaluation than is available on this site.