A member asked:

Is it known yet what component of the pfizer or moderna vaccines cause allergic reactions?

4 doctors weighed in across 2 answers
Dr. Yvette Kratzberg answered

Specializes in Pediatrics

Data is accumulating that most allergic reactions to the Covid Vaccine are mediated primarily by systemic mast cells. This is slightly different than other allergic reactions in that the allergy is based on an immune system overreaction rather than a typical histamine activation. In persons with history of anaphylaxis, vaccines should be given in a Dr's office with meds/O2 ready to counteract.

Answered 5/19/2021

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It seems to be the carrying material and not the active ingredient. Good Luck

Answered 5/19/2021

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