A member asked:

I have a labtest result concerning kappa free light chain value at 36.44 and with a lambda free light chain value of 8.66 the kappa/lambdalight ratio as a value of 4.21 i am new paitient with this ...i would like to know the stage or prognosis?

2 doctors weighed in across 2 answers

High kappa: Your elevated kappa serum free light chains&high kappa/lambda ratio is characteristic of plasma cell bone marrow pathology seen in multiple myeloma, AL amyloidosis or monoclonal gammopathy of uncertain significance. A hematologist oncologist is best to direct further testing such as bone marrow biopsy, skeletal xray survey, whole body PET scan, urine electrophoresis & immunofixation for diagnosis

Answered 1/21/2021

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Need more info: A third of people your age presenting for care have an abnormal kappa/lambda ratio. About 90% of the time it is due to elevated kappa. Your doctor can order a protein electrophoresis to find out if you have an abnormal protein. I would like to add that an abnormal protein does not always warrant treatment. See a hematologist. Wish you good health!

Answered 1/24/2021

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