I have been prescribed furazolidone for h.pylori. i am currently taking 25mg of amitriptyline a night for sleep/anxiety. there are interactions between furazolidone and amitriptyline - should i wean off amitriptyline before starting my course?

Change antibiotic: The FDA took furazolidone off the market in the United States. Combining it with amitriptyline scores an X rating on drug interaction scales due to its MAOI properties causing a potentially fatal serotonin syndrome . Safer antibiotics are available for H Pylori and increasing controversy about whether H. Pylori needs to be treated at all as it may well be a natural component of healthy gut flora