A member asked:

I received the 1st hep a immunization dose in 2013 and the 2nd in 2019. did i wait too long to get a 2nd dose? is the length of time likely to to cause my hep a antibody titer to be negative/equivocal?

4 doctors weighed in across 3 answers
Dr. Heidi Fowler answered

Specializes in Psychiatry

Hep A vaccine: See: https://patient.info/travel-and-vaccinations/travel-vaccinations-leaflet/hepatitis-a-vaccine. "A second dose of the vaccine 6-12 months after the first gives protection for about 20 years. If you are late with this second dose, you should have it as soon as possible but you don't need to start with the first dose again." This could be an issue.

Answered 6/10/2020

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Dr. Rebecca Gliksman answered

Specializes in Internal Medicine

Hep A vaccination: https://www.immunize.org/askexperts/experts_hepa.asp#:~:text=For%20long%2Dterm%20immunity%2C%20the,regardless%20of%20HAV%20exposure%20risk. What happens if dose #2 of hepatitis A vaccine is delayed? You do not need to start the series over again. The immunogenicity of 1 dose of hepatitis A vaccine is 94% to 100%. Immunogenicity is considered to be equal to efficacy; ... If worried check titers

Answered 6/18/2020

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Get a titre done? : Waiting that long between the 2 doses is definitely not recommended but many people do develop an antibody even after one dose, so you could consider having an antibody test done to be sure you are immune

Answered 6/18/2020

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