What will rid of bed bugs and soothe or just plain get rid of the biting?

Benadryl/ hydroc.: Getting rid of bed bugs effectively usually requires help from a professional exterminator with experience in bed bug control. They are very difficult to permanently get rid of on your own. There are bed bug mattress covers now available to help prevent re-infestation. Benadryl (diphenhydramine) and topical Hydrocortisone can help alleviate the intense reaction and hives that these bites can cause.

A lot of work: Declutter entire bedroom & any other effected rooms. Check this site for instructions: http://treatmentforbedbugs.Com/ place all junk in tightly sealed plastic & dispose of it. Wash clothing, linens, towels in hot water. Dry on highest heat - then repeat. Place clean items in a sealed bag to prevent re-infestation.Steam clean what you can't place in drier. Vacuum everything using a disposable.