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A member asked:
Should a man with genotype aa go ahead to marry woman with gen. ss ? if yes, any danger ?
A doctor has provided 1 answer
Sickle cell ?'s: If male genotype is normal ("AA") and female is homogenous for sickle cell disease ("SS") , any children will be "sickle cell trait" ("AS") which is not serious, and is treated if necessary if anemia develops.
Answered 9/20/2019
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