Drug interactions.: Per Drugs.Com drug interaction checker, combining metoprolol with the diphenhidramine in Tylenol PM could cause " lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate" This does not mean it would occur, it just increases the chances. Melatonin is another option for sleep.
Answered 1/28/2021
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