Can mono from ebv cause swelling of lymph nodes from head to the elbow and back of knees?

Unlikely: EBV causes lymph node swelling in the neck, usually the spleen and sometimes the liver, but in my 40 years of experience, I have not found lymph node swelling behind the knees or elbows. Lymph node enlargement in the extremities is more likely to be related to a skin condition or infection. Further evaluation is recommended if swelling doesn't resolve when other symptoms of mono resolve.