Is it safe to have one beer with dinner while on zoloft. no history of alcoholism. never even been drunk or tipsy. just enjoy one at sporting events.

Maybe/not: You will find that alcohol & Zoloft often do not get along when used together. Both enter the brain & have an effect on your nervous system. You can at least expect an amplification of the alcohols effect on you which may or may not be troublesome. You can try it with caution but be aware you may have an unhappy reaction. Be sure to have a chaperone during any trial if you go off the deep end.