My wife is 13weeks pregnant and we have done the blood test for down syndrome and the results came back with the following 1:190. please advice and give guidance on what else can we done to get a more confirmed result.

Screening v definite: You didn't provide your wife's age, which determines general DS risk, but 1/190 is elevated in general. A definitive test will require that cells from baby be examined for chromosomes. In the USA they have a test as early as 10 wks where fetal cells are found in mothers blood & studied(NIPS). Older method amnionic villus sampling or amniocentesis can do it. Unsure what is available there.