I have acid reflux but the strange thing is when im laying down my throat tightness goes away, but when im standing it comes back. ?

Rx TLESR: LES incompetence is found in only a minority of patients, and transient LES relaxations (TLESR), primarily in the upright position, are currently recognized as the main pathophysiological abnormality in gastroesophageal reflux disease, Later explains this patient symptoms in upright position vs supine. GERD with mild erosive disease could potentially benefit from anti TLESR therapy early.