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A member asked:
Can blast cells show up on cbc? why sometimes manual review is necessary?
A doctor has provided 1 answer
Yes: This is critical. Even one blast cell on peripheral smear is extremely serious. Some automated cell-counters using image analysis may mistake them for normal lymphocytes or monocytes. There's still no artificial-intelligence substitute for the human eye. If a hematologist suspects myelodysplastic syndrome, leukemia or some other myeloproliferative disease, they will look at the smear themselves.
Answered 9/18/2018
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