Can you take pristiq 50 mg and trintellix 10mg together. haven't found any sites where this is discussed.

See below: Although Pristiq and Trintellix are antidepressants with different modes of action, they both increase levels of serotonin in your system. Side effects may occur including nausea, diarrhea, agitation, fever and tremors. In worse cases, seizures may occur. Low sodium levels may also occur which could elevate the risk for seizures. Report any side effects to your Dr.

Generally NO: These 2 medication together may increase the risk of serotonin syndrome, hypo-natremia, and have other adverse or additive effects. This is not to say that in specific circumstances, where you physician appreciates all the risks, but believes it is necessary, it may be helpful to combine these 2 medications in a specific situation.