Which tablets are most highly recommended for severe headache?

Aspirin first: You can use any of the anti inflammatory agents but be aware they affect your kidney function and stomach and can cause ulcers. Use as directed. If headaches persist - you should consult a doctor.

Best Headache Meds: A 2014 study indicates that medication containing a combination of acetylsalicylic acid, (aspirin), acetaminophen(paracetamol), and caffeine is more effective than acetaminophen alone. http://thejournalofheadacheandpain.springeropen.com/articles/10.1186/1129-2377-15-76