I'm taking sertraline for anxiety and depression but i'm also taking modaifinil (100mg) to assist with study. it doesn't seem to be having much affect?

Suggestions and: modifications of psychotropic medications is best handled by YOUR health care professional since he/she knows your medical history and indications for treatment. Contact your health care provider and ask to discuss your concerns.

More mo: That is not a large dose of modafinil - it could be doubled. Zoloft (as are the other SSRI's) is reknown for causing dullness mentally, sluggish energy and even outright cognitive compromise - all reversible with dose adjustment or discontinuation. Switching to an antidepressant that does not have those effects would also be an option.