A member asked:

My doctor is switching me from sertraline to bupropion. i take 100 mg of trazodone for sleep. i read online this is a very dangerous combo. worried.

A doctor has provided 1 answer
Dr. Geoffrey Rutledge answered

Specializes in Internal Medicine

Safer combination: The possibility of a serotonin syndrome reaction to trazodone and sertraline (Zoloft) is greater than for trazodone and bupropion. So this is a safer combination to switch to.

Answered 3/29/2021

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