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A 44-year-old female asked:

my doctor is switching me from sertraline to bupropion. i take 100 mg of trazodone for sleep. i read online this is a very dangerous combo. worried.

1 doctor answer2 doctors weighed in
Dr. Geoffrey Rutledge
Internal Medicine 41 years experience
Safer combination: The possibility of a serotonin syndrome reaction to trazodone and sertraline (Zoloft) is greater than for trazodone and bupropion. So this is a safer combination to switch to.

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Last updated Mar 29, 2021

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