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A 27-year-old male asked:

Does clomipramine interfere with the efficacy of methylphenidate?

1 doctor answer6 doctors weighed in
Dr. Pierrette Mimi Poinsett
Pediatrics 39 years experience
Clomipramine: Chlormipramine is a tri-cyclic antidepressant. Drug levels of chlorimpramine may increase with taking methylphenidate at the same time. However there is no change in efficacy of methylphenidate. Your doctor is likely monitoring the effect of both medications. Ask him/her about the rationale for the drug combination.

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Last updated May 3, 2017
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