A member asked:

Can clindamycin hcl 300 mg affect the bc implant nexplanon?

A doctor has provided 1 answer
Dr. Kevin O'neil answered

Specializes in Urogynecology

Probably not: Although both etonogestrel (in nexplanon) and clindamycin are metabolized by the liver, because the etonogestrel is released subcutaneously it avoids the 'first pass' effect of liver metabolism that an oral contraceptive would be subject to. Using a condom as a backup method would certainly decrease any chance of getting pregnant, just to be safe.

Answered 4/17/2017

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