More: Genetic testing has identified genes associated with the development of polycystic kidney disease. Pkd-1 on chromosome 16 and PKD 2 on chromosome 4 cause alterations in the calcium signaling between cells of the body. 5-10 % of patients with PKD have neither gene defect. A recent paper described a PKD 3 gene but it needs to be repeated. There are also probably other gene defects involved.
Answered 1/12/2015
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