A member asked:

Can you explain ph + cml and ph neg cml?

A doctor has provided 1 answer
Dr. Michael Dugan answered

Specializes in Hematology

Ph+ refers: To the presence of a chromosome translocation between chromosome 9 and 22. Even when it is not present you can usually demonstrate at the molecular, or gene, level. The techniques are fish and pcr. Ph+ patents should respond to tyrosine kinase inhibitors.

Answered 4/12/2013

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