A member asked:

Received a depomedrol shot today 80mg, in my bottom, for allergies & sinus issues. when will it kick in and how long will it last?

A doctor has provided 1 answer
Dr. John Chiu answered

About 6 hrs: You should get some effects in about 6 hrs but the peak effect takes a day or two In general, I would advise against getting cortisone shots for a sinus infection especially for someone with anxiety & BP issues since nasal steroid likely works better with no serious side effects. If you have frequent sinusitis and allergies, best to consult an allergist.

Answered 11/22/2016

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Can allergy shots make you sleepy and give you a sinus headache?

2 doctors weighed in across 2 answers