A member asked:

I'm allergic to sulphate drugs and am currently experiencing severe abdominal pain while taking doxycycline hyclate 100 mg. i do have ibs.

A doctor has provided 1 answer
Dr. John Chiu answered

Not uncommon: Doxycycline should be taken with food to avoid this common side effects. If you still have GI problem you will need to find a substitute. By the way, the proper term is sulfa allergy not sulfate (which is not known to be allergenic) but this or IBS has nothing to do with your doxy side effect.

Answered 10/3/2016

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