A member asked:

I took an antihistamine & forgot i did. (15 min ago) came back in room & took a xanax bc i've had anxiety all day. can you mix those? should i go to t

2 doctors weighed in across 2 answers
Dr. John Chiu answered

Likely ok.: It is unlikely that you will have much problem from this. You may however get a little drowsy from the combination. No need to go to ER.

Answered 4/25/2020

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Go to.....?: You should not mix Xanax with sedating antihistamines like diphenhydramine (Benadryl) since taking them together increases the sedative effect. If your doctor OK's it, you could use a less sedating antihistamine such as loratadine (Claritin) or fexofenadine (Allegra) with Xanax. As with any habit-forming drug, you should use Xanax sparingly at the lowest effective dose. Dr. Anne

Answered 9/13/2016

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