A member asked:

Which one of ccb is better for kidney protection , bp , ankle swelling,side effects and overall safety amlodipine or lecarnidipine?

A doctor has provided 1 answer
Dr. David Lipkin answered

Specializes in Internal Medicine

Neither for kidney: Amlodipine and Lercandipine are dihydropyridines. They both can cause or increase fluid retention(edema). Neither of these agents protects kidney function if there is proteinuria present, but ACE's or ARB's will slow progression of CKD and they don't cause edema. Diltiazem and Verapamil are non dihydropyridine calcium channel blockers that don't cause edema.

Answered 9/2/2017

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