I've had vaginial irritation going on 4 weeks now and have been using vagisil cream on and off and have also been prescribed medication twice. i started to the onset of a yeast infection around the 2nd of august and my doctor prescribed me a fluconszole o

May not be yeast: If you are not responding to yeast medication then this is a sign it may not be a yeast infection. Your doctor can do a yeast culture to see if you have a type of yeast that is resistant to typical medications. They should evaluate for STDs, contact dermatitis, lichen sclerosis, lichen simplex chronicus and other vulvar disorders.