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Ada, MI
A 50-year-old female asked:

Can flexeril (cyclobenzaprine hcl) cause/trigger angioedema?

1 doctor answer2 doctors weighed in
Dr. John Shim
Orthopedic Surgery 41 years experience
Yes: Theoretically, any drug can have effects including angioedema. Having said that, it seems like a rare occurence. But, if the effect is intense, obviously you should not longer take flexeril (cyclobenzaprine hcl). Angio edema is like an allergic reaction. It can be significant, and cause breathing difficulties.

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Last updated Apr 23, 2016

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