Sinus infectipn-gene sequencing of a culture was positive for staphylococcus epidermidis mrse. are antibiotics the only way to cure the infection?

Appropriate Rx?: That seems like an unusual bacteria for sinusitis – I question the accuracy of the test. Probably that was a skin contaminant that has nothing to do with your sinusitis. Actually, the IDSA discourages antibiotic use for acute sinusitis. Would seek ID specialist or ENT. Antiinflammatory meds may help. Antibiotics could have side effects. Need to try conservative treatment first. Hope that helps.