Yes.: Chemical pleurodesis is the obliteration of the pleural space by instillation of a Tetracycline(Doxycycline or Minocycline) or Talc. The recurrence rate with Talc is 5-8 % compared with recurrence rate with Tetracycline of 20-25%. The recurrence rate with VATS is <5%. There is some concern about use of Talc in young healthty patients because of safety reasons and fear of long term health effects.
Answered 5/24/2016
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